Plasma Agouti-Related Protein Levels in Acromegaly and Effects of Surgical or Pegvisomant Therapy

CONTEXT: GH activates agouti-related protein (AgRP) neurons, leading to orexigenic responses in mice. The relationship between serum GH and plasma AgRP, which has been shown to reflect hypothalamic AgRP, has not been evaluated in humans. OBJECTIVE: To test the hypothesis that central stimulatory act...

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Publicado en:J Clin Endocrinol Metab
Autores principales: Freda, Pamela U, Reyes-Vidal, Carlos, Jin, Zhezhen, Pugh, Mya, Panigrahi, Sunil K, Bruce, Jeffrey N, Wardlaw, Sharon L
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2019
Materias:
Clinical Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777636/
https://ncbi.nlm.nih.gov/pubmed/31361303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2019-01079
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