A Synthetic Mirror Image of Kalata B1 Reveals that Cyclotide Activity Is Independent of a Protein Receptor

Featuring a circular, knotted structure and diverse bioactivities, cyclotides are a fascinating family of peptides that have inspired applications in drug design. Most likely evolved to protect plants against pests and herbivores, cyclotides also exhibit anti-cancer, anti-HIV, and hemolytic activiti...

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Veröffentlicht in:Chembiochem
Hauptverfasser: Sando, Lillian, Henriques, Sónia Troeira, Foley, Fiona, Simonsen, Shane M., Daly, Norelle L., Hall, Kristopher N., Gustafson, Kirk R., Aguilar, Marie-Isabel, Craik, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364095/
https://ncbi.nlm.nih.gov/pubmed/21928440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201100450
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