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The Biological Activity of the Prototypic Cyclotide Kalata B1 Is Modulated by the Formation of Multimeric Pores

The cyclotides are a large family of circular mini-proteins containing a cystine knot motif. They are expressed in plants as defense-related proteins, with insecticidal activity. Here we investigate their role in membrane interaction and disruption. Kalata B1, a prototypic cyclotide, was found to in...

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Détails bibliographiques
Auteurs principaux: Huang, Yen-Hua, Colgrave, Michelle L., Daly, Norelle L., Keleshian, Asbed, Martinac, Boris, Craik, David J.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742835/
https://ncbi.nlm.nih.gov/pubmed/19491108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003384
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