Orientation and Location of the Cyclotide Kalata B1 in Lipid Bilayers Revealed by Solid-State NMR

Cyclotides are ultra-stable cyclic disulfide-rich peptides from plants. Their biophysical effects and medically interesting activities are related to their membrane-binding properties, with particularly high affinity for phosphatidylethanolamine lipids. In this study we were interested in understand...

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Bibliographic Details
Published in:Biophys J
Main Authors: Grage, Stephan L., Sani, Marc-Antoine, Cheneval, Olivier, Henriques, Sónia Troeira, Schalck, Constantin, Heinzmann, Ralf, Mylne, Joshua S., Mykhailiuk, Pavel K., Afonin, Sergii, Komarov, Igor V., Separovic, Frances, Craik, David J., Ulrich, Anne S.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2017
Subjects:
Membranes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340158/
https://ncbi.nlm.nih.gov/pubmed/28256223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.12.040
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