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Optimization of the cyclotide framework to improve cell penetration properties

Cell penetrating peptides have been regarded as promising vectors to deliver hydrophilic molecules inside cells. Although they are great tools for research and have high potential as drug delivery systems, their application as drugs is impaired by their low stability in serum. Cyclotides, cyclic dis...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Huang, Yen-Hua, Chaousis, Stephanie, Cheneval, Olivier, Craik, David J., Henriques, Sónia T.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321561/
https://ncbi.nlm.nih.gov/pubmed/25709580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00017
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