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Optimization of the cyclotide framework to improve cell penetration properties

Cell penetrating peptides have been regarded as promising vectors to deliver hydrophilic molecules inside cells. Although they are great tools for research and have high potential as drug delivery systems, their application as drugs is impaired by their low stability in serum. Cyclotides, cyclic dis...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Huang, Yen-Hua, Chaousis, Stephanie, Cheneval, Olivier, Craik, David J., Henriques, Sónia T.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321561/
https://ncbi.nlm.nih.gov/pubmed/25709580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00017
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