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Optimization of the cyclotide framework to improve cell penetration properties

Cell penetrating peptides have been regarded as promising vectors to deliver hydrophilic molecules inside cells. Although they are great tools for research and have high potential as drug delivery systems, their application as drugs is impaired by their low stability in serum. Cyclotides, cyclic dis...

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Detaylı Bibliyografya
Yayımlandı:Front Pharmacol
Asıl Yazarlar: Huang, Yen-Hua, Chaousis, Stephanie, Cheneval, Olivier, Craik, David J., Henriques, Sónia T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321561/
https://ncbi.nlm.nih.gov/pubmed/25709580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00017
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