Wnt5a induces and maintains prostate cancer cells dormancy in bone

In a substantial fraction of prostate cancer (PCa) patients, bone metastasis appears after years or even decades of latency. Canonical Wnt/β-catenin signaling has been proposed to be implicated in dormancy of cancer cells. However, how these tumor cells are kept dormant and recur under control of Wn...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Ren, Dong, Dai, Yuhu, Yang, Qing, Zhang, Xin, Guo, Wei, Ye, Liping, Huang, Shuai, Chen, Xu, Lai, Yingrong, Du, Hong, Lin, Chuyong, Peng, Xinsheng, Song, Libing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363426/
https://ncbi.nlm.nih.gov/pubmed/30593464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180661
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