Copy number gain of ZEB1 mediates a double-negative feedback loop with miR-33a-5p that regulates EMT and bone metastasis of prostate cancer dependent on TGF-β signaling

Background: The reciprocal repressive loop between ZEB1 and miRNAs has been extensively reported to play an important role in tumor progression and metastasis of various human tumor types. The aim of this study was to elucidate the role and the underlying mechanism of the double-negative feedback lo...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Dai, Yuhu, Wu, Zhengquan, Lang, Chuandong, Zhang, Xin, He, Shaofu, Yang, Qing, Guo, Wei, Lai, Yingrong, Du, Hong, Peng, Xinsheng, Ren, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735523/
https://ncbi.nlm.nih.gov/pubmed/31534537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.36735
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