Copy number gain of ZEB1 mediates a double-negative feedback loop with miR-33a-5p that regulates EMT and bone metastasis of prostate cancer dependent on TGF-β signaling

Background: The reciprocal repressive loop between ZEB1 and miRNAs has been extensively reported to play an important role in tumor progression and metastasis of various human tumor types. The aim of this study was to elucidate the role and the underlying mechanism of the double-negative feedback lo...

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Podrobná bibliografie
Vydáno v:Theranostics
Hlavní autoři: Dai, Yuhu, Wu, Zhengquan, Lang, Chuandong, Zhang, Xin, He, Shaofu, Yang, Qing, Guo, Wei, Lai, Yingrong, Du, Hong, Peng, Xinsheng, Ren, Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735523/
https://ncbi.nlm.nih.gov/pubmed/31534537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.36735
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