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Negative feedback loop between p66(Shc) and ZEB1 regulates fibrotic EMT response in lung cancer cells
The epithelial-to-mesenchymal transition (EMT) program is crucial for the epithelial cancer progression and fibrotic diseases. Our previous work has demonstrated that p66(Shc), a focal adhesion-associated adaptor protein, is frequently downregulated in lung cancers and its depletion promotes metasta...
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| Publicado en: | Cell Death Dis |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4650543/ https://ncbi.nlm.nih.gov/pubmed/25837484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.74 |
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