Wnt5a induces and maintains prostate cancer cells dormancy in bone

In a substantial fraction of prostate cancer (PCa) patients, bone metastasis appears after years or even decades of latency. Canonical Wnt/β-catenin signaling has been proposed to be implicated in dormancy of cancer cells. However, how these tumor cells are kept dormant and recur under control of Wn...

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Publicado en:J Exp Med
Autores principales: Ren, Dong, Dai, Yuhu, Yang, Qing, Zhang, Xin, Guo, Wei, Ye, Liping, Huang, Shuai, Chen, Xu, Lai, Yingrong, Du, Hong, Lin, Chuyong, Peng, Xinsheng, Song, Libing
Formato: Artigo
Lenguaje:Inglês
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363426/
https://ncbi.nlm.nih.gov/pubmed/30593464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180661
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