Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology

The blood-brain barrier (BBB) has a major role in maintaining brain homeostasis through the specialized function of brain endothelial cells (BECs). Inflammation of the BECs and loss of their neuroprotective properties is associated with several neurological disorders, including the chronic neuro-inf...

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Опубликовано в: :Cell Death Dis
Главные авторы: Derada Troletti, Claudio, Fontijn, Ruud D., Gowing, Elizabeth, Charabati, Marc, van Het Hof, Bert, Didouh, Imad, van der Pol, Susanne M. A., Geerts, Dirk, Prat, Alexandre, van Horssen, Jack, Kooij, Gijs, de Vries, Helga E.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361981/
https://ncbi.nlm.nih.gov/pubmed/30718504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1294-2
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