Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier

BACKGROUND: The sphingosine 1-phosphate (S1P) receptor modulator FTY720P (Gilenya®) potently reduces relapse rate and lesion activity in the neuroinflammatory disorder multiple sclerosis. Although most of its efficacy has been shown to be related to immunosuppression through the induction of lymphop...

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Detaylı Bibliyografya
Asıl Yazarlar: van Doorn, Ruben, Lopes Pinheiro, Melissa A, Kooij, Gijs, Lakeman, Kim, van het Hof, Bert, van der Pol, Susanne MA, Geerts, Dirk, van Horssen, Jack, van der Valk, Paul, van der Kam, Elizabeth, Ronken, Eric, Reijerkerk, Arie, de Vries, Helga E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425155/
https://ncbi.nlm.nih.gov/pubmed/22715976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-133
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