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Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier
BACKGROUND: The sphingosine 1-phosphate (S1P) receptor modulator FTY720P (Gilenya®) potently reduces relapse rate and lesion activity in the neuroinflammatory disorder multiple sclerosis. Although most of its efficacy has been shown to be related to immunosuppression through the induction of lymphop...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3425155/ https://ncbi.nlm.nih.gov/pubmed/22715976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-133 |
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