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3D Genome Structures of Single Diploid Human Cells

3D genome structures play a key role in gene regulation and cell functions. Characterization of genome structures necessitates single-cell measurements. This has been achieved for haploid cells but remained a challenge for diploid cells. Here we report a single-cell chromatin conformation capture me...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Tan, Longzhi, Xing, Dong, Chang, Chi-Han, Li, Heng, Xie, X. Sunney
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360088/
https://ncbi.nlm.nih.gov/pubmed/30166492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat5641
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