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Determining the 3D genome structure of a single mammalian cell with Dip-C

3D genome structure is highly heterogeneous among single cells and contributes to cellular functions. Our single-cell chromatin conformation capture (3C/Hi-C) technique, Dip-C, enables high-resolution (20 kb or ∼100 nm) 3D genome structure determination from single human and mouse cells. Dip-C is ro...

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Dades bibliogràfiques
Publicat a:STAR Protoc
Autor principal: Tan, Longzhi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225968/
https://ncbi.nlm.nih.gov/pubmed/34195675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100622
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