Targeted Transfection Using PEGylated Cationic Liposomes Directed Towards P-Selectin Increases siRNA Delivery into Activated Endothelial Cells

The progress in small-interfering RNA (siRNA) therapeutics depends on the development of suitable nanocarriers to perform specific and effective delivery to dysfunctional cells. In this paper, we questioned whether P-selectin, a cell adhesion molecule specifically expressed on the surface of activat...

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Veröffentlicht in:Pharmaceutics
Hauptverfasser: Constantinescu, Cristina Ana, Fuior, Elena Valeria, Rebleanu, Daniela, Deleanu, Mariana, Simion, Viorel, Voicu, Geanina, Escriou, Virginie, Manduteanu, Ileana, Simionescu, Maya, Calin, Manuela
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359248/
https://ncbi.nlm.nih.gov/pubmed/30669699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11010047
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