P-Selectin Targeted Dexamethasone-Loaded Lipid Nanoemulsions: A Novel Therapy to Reduce Vascular Inflammation

Inflammation is a common process associated with numerous vascular pathologies. We hypothesized that targeting the inflamed endothelium by coupling a peptide with high affinity for P-selectin to the surface of dexamethasone-loaded lipid nanoemulsions will highly increase their specific binding to ac...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Simion, Viorel, Constantinescu, Cristina Ana, Stan, Daniela, Deleanu, Mariana, Tucureanu, Monica Madalina, Butoi, Elena, Manduteanu, Ileana, Simionescu, Maya, Calin, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039295/
https://ncbi.nlm.nih.gov/pubmed/27703301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1625149
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