Lipopolysaccharide-induced inflammation in monocytes/macrophages is blocked by liposomal delivery of G(i)-protein inhibitor

BACKGROUND: Lipopolysaccharide (LPS) is widely recognized as a potent activator of monocytes/macrophages, and its effects include an altered production of key mediators, such as inflammatory cytokines and chemokines. The involvement of G(i) protein in mediating LPS effects has been demonstrated in m...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Tucureanu, Monica Madalina, Rebleanu, Daniela, Constantinescu, Cristina Ana, Deleanu, Mariana, Voicu, Geanina, Butoi, Elena, Calin, Manuela, Manduteanu, Ileana
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2017
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743190/
https://ncbi.nlm.nih.gov/pubmed/29317816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S150918
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