Nano-Polyplexes Mediated Transfection of Runx2-shRNA Mitigates the Osteodifferentiation of Human Valvular Interstitial Cells

Calcific aortic valve disease (CAVD) is a progressive disorder that increases in prevalence with age. An important role in aortic valve calcification is played by valvular interstitial cells (VIC), that with age or in pathological conditions acquire an osteoblast-like phenotype that advances the dis...

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Foilsithe in:Pharmaceutics
Main Authors: Voicu, Geanina, Rebleanu, Daniela, Constantinescu, Cristina Ana, Fuior, Elena Valeria, Ciortan, Letitia, Droc, Ionel, Uritu, Cristina Mariana, Pinteala, Mariana, Manduteanu, Ileana, Simionescu, Maya, Calin, Manuela
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355966/
https://ncbi.nlm.nih.gov/pubmed/32498305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060507
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