Nano-Polyplexes Mediated Transfection of Runx2-shRNA Mitigates the Osteodifferentiation of Human Valvular Interstitial Cells

Calcific aortic valve disease (CAVD) is a progressive disorder that increases in prevalence with age. An important role in aortic valve calcification is played by valvular interstitial cells (VIC), that with age or in pathological conditions acquire an osteoblast-like phenotype that advances the dis...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Voicu, Geanina, Rebleanu, Daniela, Constantinescu, Cristina Ana, Fuior, Elena Valeria, Ciortan, Letitia, Droc, Ionel, Uritu, Cristina Mariana, Pinteala, Mariana, Manduteanu, Ileana, Simionescu, Maya, Calin, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355966/
https://ncbi.nlm.nih.gov/pubmed/32498305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060507
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