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Curcumin and Solid Lipid Curcumin Particles Induce Autophagy, but Inhibit Mitophagy and the PI3K-Akt/mTOR Pathway in Cultured Glioblastoma Cells

Autophagy and the (PI3K-Akt/mTOR) signaling pathway play significant roles in glioblastoma multiforme (GBM) cell death and survival. Curcumin (Cur) has been reported to prevent several cancers, including GBM. However, the poor solubility and limited bioavailability of natural Cur limits its applicat...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Maiti, Panchanan, Scott, Jason, Sengupta, Dipanwita, Al-Gharaibeh, Abeer, Dunbar, Gary L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359162/
https://ncbi.nlm.nih.gov/pubmed/30669284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20020399
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