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Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments

The treatment of glioblastoma is challenging for the clinician, due to its chemotherapeutic resistance. Recent findings suggest that targeting glioblastoma using anti-cancer natural polyphenols is a promising strategy. In this context, curcumin and berberine have been shown to have potent anti-cance...

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Pubblicato in:PLoS One
Autori principali: Maiti, Panchanan, Plemmons, Alexandra, Dunbar, Gary L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913937/
https://ncbi.nlm.nih.gov/pubmed/31841506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225660
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