EGFR deficiency leads to impaired self-renewal and pluripotency of mouse embryonic stem cells

BACKGROUND: Self-renewal and pluripotency are considered as unwavering features of embryonic stem cells (ESCs). How ESCs regulate the self-renewal and differentiation is a central question in development and regenerative medicine research. Epidermal growth factor receptor (EGFR) was identified as a...

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Bibliografski detalji
Izdano u:PeerJ
Glavni autori: Yu, Miaoying, Wei, Yinghui, Xu, Kui, Liu, Shasha, Ma, Lei, Pei, Yangli, Hu, Yanqing, Liu, Zhiguo, Zhang, Xue, Wang, Bingyuan, Mu, Yulian, Li, Kui
Format: Artigo
Jezik:Inglês
Izdano: PeerJ Inc. 2019
Teme:
Cell Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357870/
https://ncbi.nlm.nih.gov/pubmed/30713819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.6314
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