Integrative Proteomic and Phosphoproteomic Profiling of Testis from Wip1 Phosphatase-Knockout Mice: Insights into Mechanisms of Reduced Fertility*

Mice lacking wild-type p53-induced phosphatase 1 (Wip1) display male reproductive defects including smaller testes, subfertility and spermatogenesis defects at the round- and elongating-spermatid stages. However, the molecular mechanisms underlying these abnormalities remain unclear. Here we examine...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Wei, Yinghui, Gao, Qian, Niu, Pengxia, Xu, Kui, Qiu, Yiqing, Hu, Yanqing, Liu, Shasha, Zhang, Xue, Yu, Miaoying, Liu, Zhiguo, Wang, Bingyuan, Mu, Yulian, Li, Kui
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356077/
https://ncbi.nlm.nih.gov/pubmed/30361445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000479
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