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Single-cell analyses demonstrate that a heme–GATA1 feedback loop regulates red cell differentiation
Erythropoiesis is the complex, dynamic, and tightly regulated process that generates all mature red blood cells. To understand this process, we mapped the developmental trajectories of progenitors from wild-type, erythropoietin-treated, and Flvcr1-deleted mice at single-cell resolution. Importantly,...
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| Publicat a: | Blood |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6356983/ https://ncbi.nlm.nih.gov/pubmed/30530752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-05-850412 |
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