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Synthesis and Evaluation of a Chitosan Oligosaccharide-Streptomycin Conjugate against Pseudomonas aeruginosa Biofilms

Microbial biofilms are considerably more resistant to antibiotics than planktonic cells. It has been reported that chitosan coupling with the aminoglycoside antibiotic streptomycin dramatically disrupted biofilms of several Gram-positive bacteria. This finding suggested the application of the covale...

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Dettagli Bibliografici
Pubblicato in:Mar Drugs
Autori principali: Li, Ruilian, Yuan, Xianghua, Wei, Jinhua, Zhang, Xiafei, Cheng, Gong, Wang, Zhuo A., Du, Yuguang
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356912/
https://ncbi.nlm.nih.gov/pubmed/30634609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17010043
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