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Synthesis and Evaluation of a Chitosan Oligosaccharide-Streptomycin Conjugate against Pseudomonas aeruginosa Biofilms

Microbial biofilms are considerably more resistant to antibiotics than planktonic cells. It has been reported that chitosan coupling with the aminoglycoside antibiotic streptomycin dramatically disrupted biofilms of several Gram-positive bacteria. This finding suggested the application of the covale...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Li, Ruilian, Yuan, Xianghua, Wei, Jinhua, Zhang, Xiafei, Cheng, Gong, Wang, Zhuo A., Du, Yuguang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356912/
https://ncbi.nlm.nih.gov/pubmed/30634609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17010043
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