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On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation

The DNA damage response (DDR) is a designation for a number of pathways that protects our DNA from various damaging agents. In normal cells, the DDR is extremely important for maintaining genome integrity, but in cancer cells these mechanisms counteract therapy-induced DNA damage. Inhibition of the...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: van den Tempel, Nathalie, Zelensky, Alex N., Odijk, Hanny, Laffeber, Charlie, Schmidt, Christine K., Brandsma, Inger, Demmers, Jeroen, Krawczyk, Przemek M., Kanaar, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356811/
https://ncbi.nlm.nih.gov/pubmed/30650591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010097
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