HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells

The hypoxia-inducible transcription factors (HIF)-1/2α are the main oxygen sensors which regulate the adaptation to intratumoral hypoxia. The aim of this study was to assess the role of the HIF proteins in regulating the radiation response of a non-small cell lung cancer (NSCLC) in vitro model. To d...

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Udgivet i:Cells
Main Authors: Moreno Roig, Eloy, Groot, Arjan J., Yaromina, Ala, Hendrickx, Tessa C., Barbeau, Lydie M. O., Giuranno, Lorena, Dams, Glenn, Ient, Jonathan, Olivo Pimentel, Veronica, van Gisbergen, Marike W., Dubois, Ludwig J., Vooijs, Marc A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356534/
https://ncbi.nlm.nih.gov/pubmed/30642030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8010045
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