Varlitinib Downregulates HER/ERK Signaling and Induces Apoptosis in Triple Negative Breast Cancer Cells

Triple-negative breast cancer (TNBC) is a complex disease associated with the aggressive phenotype and poor prognosis. TNBC harbors heterogeneous molecular subtypes with no approved specific targeted therapy. It has been reported that HER receptors are overexpressed in breast cancer including TNBC....

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Liu, Chun-Yu, Chu, Pei-Yi, Huang, Chun-Teng, Chen, Ji-Lin, Yang, Hsiu-Ping, Wang, Wan-Lun, Lau, Ka-Yi, Lee, Chia-Han, Lan, Tien-Yun, Huang, Tzu-Ting, Lin, Po-Han, Dai, Ming-Shen, Tseng, Ling-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356324/
https://ncbi.nlm.nih.gov/pubmed/30658422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010105
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