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Regulators of Oncogenic Mutant TP53 Gain of Function
The tumor suppressor p53 (TP53) is the most frequently mutated human gene. Mutations in TP53 not only disrupt its tumor suppressor function, but also endow oncogenic gain-of-function (GOF) activities in a manner independent of wild-type TP53 (wtp53). Mutant TP53 (mutp53) GOF is mainly mediated by it...
Gardado en:
| Publicado en: | Cancers (Basel) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6356290/ https://ncbi.nlm.nih.gov/pubmed/30577483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010004 |
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