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Regulators of Oncogenic Mutant TP53 Gain of Function
The tumor suppressor p53 (TP53) is the most frequently mutated human gene. Mutations in TP53 not only disrupt its tumor suppressor function, but also endow oncogenic gain-of-function (GOF) activities in a manner independent of wild-type TP53 (wtp53). Mutant TP53 (mutp53) GOF is mainly mediated by it...
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| 出版年: | Cancers (Basel) |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6356290/ https://ncbi.nlm.nih.gov/pubmed/30577483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010004 |
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