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Control of Nucleotide Metabolism Enables Mutant p53’s Oncogenic Gain-of-Function Activity
Since its discovery as an oncoprotein in 1979, investigation into p53’s many identities has completed a full circle and today it is inarguably the most extensively studied tumor suppressor (wild-type p53 form or WTp53) and oncogene (mutant p53 form or mtp53) in cancer research. After the p53 protein...
Guardat en:
| Publicat a: | Int J Mol Sci |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5751358/ https://ncbi.nlm.nih.gov/pubmed/29257071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18122759 |
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