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TFEB controls vascular development by regulating the proliferation of endothelial cells

Transcription factor TFEB is thought to control cellular functions—including in the vascular bed—primarily via regulation of lysosomal biogenesis and autophagic flux. Here, we report that TFEB also orchestrates a non‐canonical program that controls the cell cycle/VEGFR2 pathway in the developing vas...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Doronzo, Gabriella, Astanina, Elena, Corà, Davide, Chiabotto, Giulia, Comunanza, Valentina, Noghero, Alessio, Neri, Francesco, Puliafito, Alberto, Primo, Luca, Spampanato, Carmine, Settembre, Carmine, Ballabio, Andrea, Camussi, Giovanni, Oliviero, Salvatore, Bussolino, Federico
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356157/
https://ncbi.nlm.nih.gov/pubmed/30591554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798250
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