TFEB controls vascular development by regulating the proliferation of endothelial cells

Transcription factor TFEB is thought to control cellular functions—including in the vascular bed—primarily via regulation of lysosomal biogenesis and autophagic flux. Here, we report that TFEB also orchestrates a non‐canonical program that controls the cell cycle/VEGFR2 pathway in the developing vas...

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Udgivet i:EMBO J
Main Authors: Doronzo, Gabriella, Astanina, Elena, Corà, Davide, Chiabotto, Giulia, Comunanza, Valentina, Noghero, Alessio, Neri, Francesco, Puliafito, Alberto, Primo, Luca, Spampanato, Carmine, Settembre, Carmine, Ballabio, Andrea, Camussi, Giovanni, Oliviero, Salvatore, Bussolino, Federico
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356157/
https://ncbi.nlm.nih.gov/pubmed/30591554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798250
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