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The individual components of commercial isometamidium do not possess stronger trypanocidal activity than the mixture, nor bypass isometamidium resistance

The four components present in the trypanocidal treatment Samorin, the commercially available formulation of isometamidium, were separated and purified by column chromatography. These compounds as well as the Samorin mixture and the other phenanthridine trypanocide, homidium, were tested on Trypanos...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Eze, Anthonius A., Igoli, John, Gray, Alexander I., Skellern, Graham G., De Koning, Harry P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356087/
https://ncbi.nlm.nih.gov/pubmed/30685630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2019.01.003
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