R‐loop formation during S phase is restricted by PrimPol‐mediated repriming

During DNA replication, conflicts with ongoing transcription are frequent and require careful management to avoid genetic instability. R‐loops, three‐stranded nucleic acid structures comprising a DNA:RNA hybrid and displaced single‐stranded DNA, are important drivers of damage arising from such conf...

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Detaylı Bibliyografya
Yayımlandı:EMBO J
Asıl Yazarlar: Šviković, Saša, Crisp, Alastair, Tan‐Wong, Sue Mei, Guilliam, Thomas A, Doherty, Aidan J, Proudfoot, Nicholas J, Guilbaud, Guillaume, Sale, Julian E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356060/
https://ncbi.nlm.nih.gov/pubmed/30478192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899793
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