High-fat diet disturbs lipid raft/TGF-β signaling-mediated maintenance of hematopoietic stem cells in mouse bone marrow

Despite recent in vivo data demonstrating that high-fat diet (HFD)-induced obesity leads to major perturbations in murine hematopoietic stem cells (HSC), the direct role of a HFD is not yet completely understood. Here, we investigate the direct impact of a short-term HFD on HSC and hematopoiesis in...

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Vydáno v:Nat Commun
Hlavní autoři: Hermetet, François, Buffière, Anne, Aznague, Aziza, Pais de Barros, Jean-Paul, Bastie, Jean-Noël, Delva, Laurent, Quéré, Ronan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355776/
https://ncbi.nlm.nih.gov/pubmed/30705272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08228-0
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