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Hepatic thrombopoietin is required for bone marrow hematopoietic stem cell maintenance
Hematopoietic stem cell (HSC) maintenance depends on extrinsic cues. Currently, only local signals arising from the bone marrow niche have been shown to maintain HSCs. However, it is not known whether systemic factors also sustain HSCs. We assessed the physiological source of thrombopoietin (TPO), a...
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| Udgivet i: | Science |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5930357/ https://ncbi.nlm.nih.gov/pubmed/29622652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aap8861 |
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