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Leptin receptor-expressing bone marrow stromal cells are myofibroblasts in primary myelofibrosis
Bone marrow fibrosis is a critical component of primary myelofibrosis (PMF). But the origin of myofibroblasts that drive fibrosis is unknown. Using genetic fate mapping we found that bone marrow Leptin receptor (Lepr) – expressing mesenchymal stromal lineage cells expanded extensively and were the f...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5801040/ https://ncbi.nlm.nih.gov/pubmed/28481328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3530 |
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