Persistent IDH1/2 mutations in remission can predict relapse in patients with acute myeloid leukemia

Persistence of IDH1 or IDH2 mutations in remission bone marrow specimens of patients with acute myeloid leukemia has been observed, but the clinical impact of these mutations is not well known. In this study, we evaluated 80 acute myeloid leukemia patients with known IDH1 R132 or IDH2 R140/R172 muta...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Ok, Chi Young, Loghavi, Sanam, Sui, Dawen, Wei, Peng, Kanagal-Shamanna, Rashmi, Yin, C. Cameron, Zuo, Zhuang, Routbort, Mark J., Tang, Guilin, Tang, Zhenya, Jorgensen, Jeffrey L., Luthra, Rajyalakshmi, Ravandi, Farhad, Kantarjian, Hagop M., DiNardo, Courtney D., Medeiros, L. Jeffrey, Wang, Sa A., Patel, Keyur P.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355476/
https://ncbi.nlm.nih.gov/pubmed/30171025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.191148
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