Next-generation sequencing-based multigene mutational screening for acute myeloid leukemia using MiSeq: applicability for diagnostics and disease monitoring

Routine molecular testing in acute myeloid leukemia involves screening several genes of therapeutic and prognostic significance for mutations. A comprehensive analysis using single-gene assays requires large amounts of DNA, is cumbersome and timely consolidation of results for clinical reporting is...

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Päätekijät: Luthra, Rajyalakshmi, Patel, Keyur P., Reddy, Neelima G., Haghshenas, Varan, Routbort, Mark J., Harmon, Michael A., Barkoh, Bedia A., Kanagal-Shamanna, Rashmi, Ravandi, Farhad, Cortes, Jorge E, Kantarjian, Hagop M, Medeiros, L. Jeffrey, Singh, Rajesh R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ferrata Storti Foundation 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943309/
https://ncbi.nlm.nih.gov/pubmed/24142997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.093765
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