Mutational Profiling of Therapy-related Myelodysplastic Syndromes and Acute Myeloid Leukemia by Next Generation Sequencing, a Comparison with de novo Diseases

In this study we used a next generation sequencing-based approach to profile gene mutations in therapy-related myelodysplastic syndromes (t-MDS) and acute myeloid leukemia (t-AML); and compared these findings with de novo MDS/AML. Consecutive bone marrow samples of 498 patients, including 70 therapy...

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Detalhes bibliográficos
Publicado no:Leuk Res
Main Authors: Ok, Chi Young, Patel, Keyur P., Garcia-Manero, Guillermo, Routbort, Mark J., Fu, Bin, Tang, Guilin, Goswami, Maitrayee, Singh, Rajesh, Kanagal-Shamanna, Rashmi, Pierce, Sherry A., Young, Ken H., Kantarjian, Hagop M., Medeiros, L. Jeffrey, Luthra, Rajyalakshmi, Wang, Sa A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548131/
https://ncbi.nlm.nih.gov/pubmed/25573287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2014.12.006
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