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Acute Myeloid Leukemia with IDH1 or IDH2 Mutations: Frequency and Clinicopathologic Features

Mutations in the isocitrate dehydrogenase 1 (IDH1) and IDH2 genes are reported recently in AML. Here we investigate the frequency and the clinicopathologic features of IDH1 and IDH2 mutations in AML. Mutations in IDH1 (IDH1(R132)) and IDH2 (IDH2(R172)) were assessed by Sanger sequencing in 199 AML c...

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Bibliografski detalji
Izdano u:Am J Clin Pathol
Glavni autori: Patel, Keyur P., Ravandi, Farhad, Ma, Deqin, Paladugu, Abhaya, Barkoh, Bedia A., Medeiros, L. Jeffrey, Luthra, Rajyalakshmi
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465954/
https://ncbi.nlm.nih.gov/pubmed/21173122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1309/AJCPD7NR2RMNQDVF
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