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Characteristics, clinical outcome, and prognostic significance of IDH mutations in AML

The pathophysiology of IDH mutations in tumorigenesis is increasingly described, yet the prognostic significance of IDH1 and IDH2 mutations in AML remains controversial. The primary objective of this study was to define the natural history and prognosis of patients with AML and IDH1 or IDH2 mutation...

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Podrobná bibliografie
Vydáno v:Am J Hematol
Hlavní autoři: DiNardo, Courtney D., Ravandi, Farhad, Agresta, Sam, Konopleva, Marina, Takahashi, Koichi, Kadia, Tapan, Routbort, Mark, Patel, Keyur P., Brandt, Mark, Pierce, Sherry, Garcia-Manero, Guillermo, Cortes, Jorge, Kantarjian, Hagop
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612499/
https://ncbi.nlm.nih.gov/pubmed/26016821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.24072
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