Characteristics, clinical outcome, and prognostic significance of IDH mutations in AML

The pathophysiology of IDH mutations in tumorigenesis is increasingly described, yet the prognostic significance of IDH1 and IDH2 mutations in AML remains controversial. The primary objective of this study was to define the natural history and prognosis of patients with AML and IDH1 or IDH2 mutation...

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Bibliografske podrobnosti
izdano v:Am J Hematol
Main Authors: DiNardo, Courtney D., Ravandi, Farhad, Agresta, Sam, Konopleva, Marina, Takahashi, Koichi, Kadia, Tapan, Routbort, Mark, Patel, Keyur P., Brandt, Mark, Pierce, Sherry, Garcia-Manero, Guillermo, Cortes, Jorge, Kantarjian, Hagop
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612499/
https://ncbi.nlm.nih.gov/pubmed/26016821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.24072
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