Characteristics, clinical outcome, and prognostic significance of IDH mutations in AML

The pathophysiology of IDH mutations in tumorigenesis is increasingly described, yet the prognostic significance of IDH1 and IDH2 mutations in AML remains controversial. The primary objective of this study was to define the natural history and prognosis of patients with AML and IDH1 or IDH2 mutation...

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Publicado en:Am J Hematol
Autores principales: DiNardo, Courtney D., Ravandi, Farhad, Agresta, Sam, Konopleva, Marina, Takahashi, Koichi, Kadia, Tapan, Routbort, Mark, Patel, Keyur P., Brandt, Mark, Pierce, Sherry, Garcia-Manero, Guillermo, Cortes, Jorge, Kantarjian, Hagop
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612499/
https://ncbi.nlm.nih.gov/pubmed/26016821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.24072
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