Prognostic Significance of Alterations in IDH Enzyme Isoforms in Patients With AML Treated With High Dose Cytarabine and Idarubicin

BACKGROUND: IDH1 and IDH2 gene mutations are novel, recurring molecular aberrations among patients with normal karyotype acute myeloid leukemia (AML). METHODS: Among 358 patients with AML treated on 4 protocols using high dose ara-C plus idarubicin induction, pre-treatment samples were available for...

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Main Authors: Ravandi, Farhad, Patel, Keyur, Luthra, Rajyalakshmi, Faderl, Stefan, Konopleva, Marina, Kadia, Tapan, Brandt, Mark, Pierce, Sherry, Kornblau, Steven, Andreeff, Michael, Wang, Xuemei, Garcia-Manero, Guillermo, Cortes, Jorge, Kantarjian, Hagop
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060157/
https://ncbi.nlm.nih.gov/pubmed/22020636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26580
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