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EGFR/uPAR interaction as druggable target to overcome vemurafenib acquired resistance in melanoma cells
BACKGROUND: BRAF inhibitor (BRAF-I) therapy for melanoma patients harboring the V600E mutation is initially highly effective, but almost all patients relapse within a few months. Understanding the molecular mechanisms behind BRAF-I responsiveness and acquired resistance is therefore an important iss...
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| Publicado no: | EBioMedicine |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355443/ https://ncbi.nlm.nih.gov/pubmed/30611716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.12.024 |
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