Lipid transporter Spns2 promotes microglia pro-inflammatory activation in response to amyloid-beta peptide

Accumulating evidence indicates that neuroinflammation contributes to the pathogenesis and exacerbation of neurodegenerative disorders, such as Alzheimer disease (AD). Sphingosine-1-phosphate (S1P) is a pleiotropic bioactive lipid that regulates many pathophysiological processes including inflammati...

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Bibliografske podrobnosti
izdano v:Glia
Main Authors: Zhong, Liansheng, Jiang, Xue, Zhu, Zhihui, Qin, Haiyan, Dinkins, Michael B., Kong, Ji-Na, Leanhart, Silvia, Wang, Rebecca, Elsherbini, Ahmed, Bieberich, Erhard, Zhao, Yujie, Wang, Guanghu
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355341/
https://ncbi.nlm.nih.gov/pubmed/30484906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23558
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