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Critical Role of Spns2, a Sphingosine-1-Phosphate Transporter, in Lung Cancer Cell Survival and Migration

The sphingosine-1-phosphate (S1P) transporter Spns2 regulates myocardial precursor migration in zebrafish and lymphocyte trafficking in mice. However, its function in cancer has not been investigated. We show here that ectopic Spns2 expression induced apoptosis and its knockdown enhanced cell migrat...

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Bibliografiske detaljer
Main Authors: Bradley, Eric, Dasgupta, Somsankar, Jiang, Xue, Zhao, Xiaying, Zhu, Gu, He, Qian, Dinkins, Michael, Bieberich, Erhard, Wang, Guanghu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203763/
https://ncbi.nlm.nih.gov/pubmed/25330231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110119
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