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Critical Role of Spns2, a Sphingosine-1-Phosphate Transporter, in Lung Cancer Cell Survival and Migration

The sphingosine-1-phosphate (S1P) transporter Spns2 regulates myocardial precursor migration in zebrafish and lymphocyte trafficking in mice. However, its function in cancer has not been investigated. We show here that ectopic Spns2 expression induced apoptosis and its knockdown enhanced cell migrat...

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Bibliografiska uppgifter
Huvudupphovsmän: Bradley, Eric, Dasgupta, Somsankar, Jiang, Xue, Zhao, Xiaying, Zhu, Gu, He, Qian, Dinkins, Michael, Bieberich, Erhard, Wang, Guanghu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203763/
https://ncbi.nlm.nih.gov/pubmed/25330231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110119
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