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Critical Role of Spns2, a Sphingosine-1-Phosphate Transporter, in Lung Cancer Cell Survival and Migration

The sphingosine-1-phosphate (S1P) transporter Spns2 regulates myocardial precursor migration in zebrafish and lymphocyte trafficking in mice. However, its function in cancer has not been investigated. We show here that ectopic Spns2 expression induced apoptosis and its knockdown enhanced cell migrat...

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Detaylı Bibliyografya
Asıl Yazarlar: Bradley, Eric, Dasgupta, Somsankar, Jiang, Xue, Zhao, Xiaying, Zhu, Gu, He, Qian, Dinkins, Michael, Bieberich, Erhard, Wang, Guanghu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203763/
https://ncbi.nlm.nih.gov/pubmed/25330231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110119
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